Recurrent aphthous stomatitis and atopy

Autor: Stefano Rosin, Gianni Bezze, Cleto Veller-Fornasa, Marco Tarantello, Roberto Cipriani, Michela Lazzaro
Rok vydání: 2003
Předmět:
Zdroj: Acta dermato-venereologica. 83(6)
ISSN: 0001-5555
Popis: Sir, Recurrent aphthous stomatitis (RAS) is the appearance of recidivant aphthae, almost exclusively in the oral cavity. Atopy is defined as a genetically determined disorder in which there is an increased likelihood of IgE antibodies forming, and an increased susceptibility to diseases such as asthma, hay fever and atopic dermatitis (1). RAS can be part of the symptoms in Behcet disease, Sweet syndrome and Crohn disease, but often it is idiopathic. Atopy can have a significant association with other immunological mediated diseases, e.g. alopecia areata (1, 2). Of added interest is the fact that the pathology of the aphthae involves many signs of immunological complexity (1, 3). Additionally, there are many reports correlating RAS with food allergy or food intolerance (FA/FI) (4 – 9). Based on this multifaceted background of RAS, we decided to investigate whether patients affected byRAS present clinical manifestations of atopy or have an atopic background.
Databáze: OpenAIRE