Tribulus terrestris Efficacy and Safety Concerns in Diabetes and Erectile Dysfunction, Assessed in an Experimental Model
| Autor: | Adina Huțanu, Camil Eugen Vari, Ancuța Negroiu, Lenard Farczadi, Marius Mărușteri, Ruxandra Ștefănescu, Bianca E. Ősz |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Tribulus terrestris erectile dysfunction medicine.medical_treatment Protodioscin Plant Science Article 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Internal medicine Diabetes mellitus medicine Ecology Evolution Behavior and Systematics Testosterone steroidal saponins 030219 obstetrics & reproductive medicine Ecology diabetes Experimental model business.industry Insulin Botany medicine.disease 030104 developmental biology Erectile dysfunction Endocrinology chemistry QK1-989 Luteinizing hormone business |
| Zdroj: | Plants Volume 10 Issue 4 Plants, Vol 10, Iss 744, p 744 (2021) |
| ISSN: | 2223-7747 |
| Popis: | The present project aims to evaluate Tribulus terrestris (TT) extracts by addressing various possible mechanisms of action in order to see whether the use of TT supplements in diabetes and diabetes complications is justified. Diabetic rats were divided into three groups: diabetic control group, TT extract with low protodioscin content group (TT-LPC) and TT extract with high protodioscin content group (TT-HPC). After twelve weeks of treatment, fasting blood glucose, insulin, LH, FSH and testosterone levels were measured. Both TT preparations reduced elevated blood glucose level. Insulin and luteinizing hormone levels were not significantly different compared with the control group however, the FSH and testosterone levels were significantly higher in the TT-HPC group compared with the diabetic control group. The testosterone level is correlated in part with the protodioscin concentration in extracts and is probably mediated through an FSH-linked pathway. |
| Databáze: | OpenAIRE |
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