Clinical assessment of sacroiliitis and HLA-B27 are poor predictors of sacroiliitis diagnosed by magnetic resonance imaging in psoriatic arthritis
| Autor: | L Williamson, Eugene McNally, J L Dockerty, B P Wordsworth, S. Ostlere, N. Dalbeth |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Adult
Male medicine.medical_specialty Population Arthritis Psoriatic arthritis Rheumatology Predictive Value of Tests Internal medicine Prevalence Medicine Humans Pharmacology (medical) education HLA-B27 Antigen Aged Sacroiliac joint education.field_of_study HLA-B27 medicine.diagnostic_test business.industry Arthritis Psoriatic Sacroiliitis Magnetic resonance imaging Sacroiliac Joint Middle Aged medicine.disease Magnetic Resonance Imaging Surgery medicine.anatomical_structure Female Radiology business |
| Popis: | Objective To determine the frequency and clinical predictors of sacroiliitis diagnosed by magnetic resonance imaging (MRI) in a psoriatic arthritis (PsA) population. Methods The studied comprised 103 patients with PsA. A careful clinical assessment for sacroiliitis was made from history and examination, and HLA-B27 testing was performed. Sixty-eight patients underwent tilted coronal fat-saturated T1-weighted and STIR MRI of the sacroiliac joints. Results Clinical features of moderate or severe sacroiliitis were found in 24/68 (35%) patients. MRI features of sacroiliitis were found in 26/68 (38%) patients. Clinical features of sacroiliitis were present in 14/42 (33%) with normal MRI scans and 10/26 (38%) with abnormal scans (normal vs abnormal scans, P = 0.7). The presence of sacroiliitis on MRI was associated with restricted spinal movements (P = 0.004) and the duration of PsA (P = 0.04). There was no correlation between HLA-B27 and sacroiliitis diagnosed by MRI. Conclusion Sacroiliitis diagnosed by MRI occurs commonly in PsA but is difficult to detect clinically. |
| Databáze: | OpenAIRE |
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