Tubular Excretion of Serotonin (5-Hydroxytryptamine) in the Chicken

Autor:	Erland Sanner, Bernard Wortman
Rok vydání:	1962
Předmět:	Serotonin medicine.medical_specialty Amine oxidase Meat Monoamine Oxidase Inhibitors Physiology Tubular excretion Chemistry Reserpine Kidney Excretion Intravenous use Endocrinology Renal physiology Internal medicine medicine Animals Humans Urine flow Chickens medicine.drug
Zdroj:	Acta Physiologica Scandinavica. 55:319-324
ISSN:	1365-201X 0001-6772
DOI:	10.1111/j.1748-1716.1962.tb02446.x
Popis:	Serotonin at a dose of 200 μg given to normal chickens by unilateral leg vein infusion showed an ipsilateral excess of excretion. The excess excretion was below 10 per cent of the dose however. Birds pretreated with a mono amine oxidase inhibitor showed an ipsilateral excess of such a magnitude (26 per cent of the injected dose) that it proves a tubular excretion of serotonin. Reserpine failed to block this process, but a small blocking effect of reserpine cannot be excluded. Urine flow was not significantly altered by the dose of serotonin used in this study.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb519078217258f5dc731188c9583198 https://doi.org/10.1111/j.1748-1716.1962.tb02446.x Zobrazit plný text záznamu Plný text