Immunoepidemiologic studies of Strongyloides stercoralis and human T lymphotropic virus type I infections in Jamaica
| Autor: | S. I. Terry, F. A. Neva, R. D. Robinson, John F. Lindo, A. A. Gam, P. Vogel, E. S. Cooper |
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| Rok vydání: | 1994 |
| Předmět: |
Adult
Male Jamaica Helminthiasis Human T-lymphotropic virus Immunoglobulin E Virus Strongyloides stercoralis medicine Prevalence Immunology and Allergy Animals Humans biology business.industry biology.organism_classification medicine.disease HTLV-I Infections Infectious Diseases Strongyloidiasis Immunology biology.protein Female Viral disease Antibody business |
| Zdroj: | The Journal of infectious diseases. 169(3) |
| ISSN: | 0022-1899 |
| Popis: | Epidemiologic investigations of Strongyloides stercoralis and human T lymphotropic virus type I (HTLV-I) infections were conducted. Of 312 persons contacted, 209 (67%) provided blood and stool samples. Prevalences of S. stercoralis and HTLV-I antibodies were 26.8% and 8.1% (n = 198), respectively, and S. stercoralis larvae were detected in 4%. HTLV-I antibodies were significantly more common in persons positive for S. stercoralis larvae (10 [58.8%] of 17) compared with seropositive larva-negative (4 [8.9%] of 45) or seronegative persons (9 [6.2%] of 145) (P < .002). IgE levels increased with age in S. stercoralis-seropositive persons who were HTLV-I negative (P < .002). However, there was an age-related depression of serum IgE in HTLV-I-positive positive persons (P < .003) that was sufficient to annul the IgE level-raising effect of S. stercoralis seropositivity. The data provide evidence that HTLV-I infection is associated with increased frequency of larvae in the stool of S. stercoralis-infected persons and suggest that the mechanism may involve suppression of the IgE response. |
| Databáze: | OpenAIRE |
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