Effectivity of laser-induced thermotherapy: in vivo comparison of arterial microembolization and complete hepatic inflow occlusion
| Autor: | C. Isbert, Kai S. Lehmann, Joerg-Peter Ritz, Andre Roggan, Heinz J. Buhr, Christoph T. Germer |
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| Rok vydání: | 2005 |
| Předmět: |
Male
medicine.medical_specialty Percutaneous Laser-induced thermotherapy Swine Dermatology Dissection (medical) Lesion Hepatic Artery In vivo Occlusion medicine Animals business.industry Liver Neoplasms Starch Blood flow medicine.disease Embolization Therapeutic Microspheres Disease Models Animal Surgery Radiology Laser Therapy medicine.symptom Nuclear medicine business Perfusion Liver Circulation |
| Zdroj: | Lasers in surgery and medicine. 36(3) |
| ISSN: | 0196-8092 |
| Popis: | Background and Objectives Laser-induced thermotherapy (LITT) is a promising method for local treatment of liver metastases. The aim of this study was to compare the effect of LITT on lesion size when combined with hepatic arterial microembolization or complete hepatic blood flow occlusion. Study Design/Materials and Methods In a porcine liver model, LITT (30 W 15 minutes) was performed with either normal (n = 12), partially interrupted (arterial microembolization via a hepatic artery catheter n = 12) or completely interrupted hepatic perfusion (Pringle's maneuver, n = 12). LITT lesions were macro- and microscopically assessed after liver dissection. Results Hepatic inflow occlusion led to a fourfold increase in lesion volume after arterial microembolization and a ninefold increase after complete interruption (6.3. cm3 vs. 27.1 cm3 vs. 58.8 cm3, P |
| Databáze: | OpenAIRE |
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