Lymphoid cells in lymph nodes and peripheral blood of patients with squamous cell carcinoma of the head and neck
| Autor: | Cachin Y, P. C. Quan, Ch. Micheau, F. Bekkoucha, R. Roubin, M.-C. Fondaneche, P. Burtin |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
Adult
Male Cancer Research Pathology medicine.medical_specialty Phagocytosis T-Lymphocytes Acid Phosphatase Leukocyte Count Internal medicine medicine Carcinoma Macrophage Humans Aged Hematology business.industry Macrophages Cancer General Medicine Middle Aged medicine.disease Peripheral blood Lymphatic system Oncology Head and Neck Neoplasms Lymphatic Metastasis Carcinoma Squamous Cell Female Lymph Lymph Nodes business |
| Zdroj: | Journal of cancer research and clinical oncology. 102(3) |
| ISSN: | 0171-5216 |
| Popis: | Fifty-five patients with squamous cell carcinoma of the head and neck were evaluated immunologically by measuring the level of T cells (E-RFC) and high affinity subset T cells (E-29) in the peripheral blood and peritumorous lymph nodes. A significant decrease (p less than 0.05) in mean percentage of E-29 was observed in cancer patient peripheral blood. In peritumorous lymph nodes, there was no difference in terms of total T cells or of high affinity subset T cells, as compared to non-malignant lymph nodes, or between tumor-free and metastatic lymph nodes. Macrophage content was much higher in metastatic than in tumor-free lymph nodes (p less than 0.05) and these macrophages frequently appeared to be more active when tested in phagocytosis of sheep red blood cells sensitized with IgG or IgM + C. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink