Comparison of the analytic sensitivities of a recombinant immunoblot assay and the radioimmune precipitation assay for the detection of antibodies to Trypanosoma cruzi in patients with Chagas disease
| Autor: | Benedict A. Marchlewicz, Dinesh O. Shah, Kevin Y. Cheng, Louis V. Kirchhoff, Chi-Deu Chang, Vince A. Salbilla, Neeraj Adya |
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| Rok vydání: | 2010 |
| Předmět: |
Microbiology (medical)
Chagas disease Trypanosoma cruzi Immunoblotting Radioimmunoassay Antibodies Protozoan Sensitivity and Specificity law.invention law parasitic diseases medicine Humans Immunoblot Assay Chagas Disease biology Kinetoplastida General Medicine biology.organism_classification medicine.disease Virology Infectious Diseases Recombinant DNA biology.protein Protozoa Parasitology Antibody Trypanosomiasis |
| Zdroj: | Diagnostic Microbiology and Infectious Disease. 67:402-405 |
| ISSN: | 0732-8893 |
| DOI: | 10.1016/j.diagmicrobio.2010.03.013 |
| Popis: | The diagnosis of chronic Chagas disease usually is made by detecting antibodies to Trypanosoma cruzi, the protozoan parasite that causes this illness. A highly sensitive and specific immunoblot assay developed by us showed a higher analytic sensitivity than the radioimmune precipitation assay, which is used widely as a confirmatory test. |
| Databáze: | OpenAIRE |
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