The influence of hay steaming on clinical signs and airway immune response in severe asthmatic horses

Autor: Stéphane Pronost, Céline Bizon-Mercier, Eric Richard, Laurent L. Couëtil, Romain Paillot, Magali Demoor, Marie Orard, Anne Couroucé, Erika Hue, Marie-Pierre Toquet, Meriel Moore-Colyer
Přispěvatelé: LABÉO, Pôle d’analyses et de recherche de Normandie (LABÉO), Biologie, génétique et thérapies ostéoarticulaires et respiratoires (BIOTARGEN), Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU), Ecole Nationale Vétérinaire, Agroalimentaire et de l'alimentation Nantes-Atlantique (ONIRIS), PRES Université Nantes Angers Le Mans (UNAM), Royal Agricultural University (RAU), College of Veterinary Medicine, Purdue University [West Lafayette]
Rok vydání: 2018
Předmět:
Male
0301 basic medicine
medicine.medical_specialty
040301 veterinary sciences
Air Microbiology
Inflammation
Gastroenterology
Equine asthma
0403 veterinary science
03 medical and health sciences
Internal medicine
Cytology
medicine
Animals
Horses
Respiratory system
Asthma
lcsh:Veterinary medicine
[SDV.BA.MVSA]Life Sciences [q-bio]/Animal biology/Veterinary medicine and animal Health
General Veterinary
medicine.diagnostic_test
business.industry
Hay steaming
04 agricultural and veterinary sciences
General Medicine
respiratory system
Airway obstruction
medicine.disease
Animal Feed
Mucus
Trachea
Steam
030104 developmental biology
Bronchoalveolar lavage
Hay
lcsh:SF600-1100
[SDV.IMM]Life Sciences [q-bio]/Immunology
Cytokines
Female
Horse Diseases
medicine.symptom
business
Bronchoalveolar Lavage Fluid
Research Article
Zdroj: BMC Veterinary Research
BMC Veterinary Research, BioMed Central, 2018, 14 (1), pp.345. ⟨10.1186/s12917-018-1636-4⟩
BMC Veterinary Research, Vol 14, Iss 1, Pp 1-11 (2018)
ISSN: 1746-6148
DOI: 10.1186/s12917-018-1636-4
Popis: Background Avoidance of antigenic stimuli was found to significantly reverse airway obstruction of horses with severe equine asthma (sEA). To date, no published study investigated the influence of steaming hay on lower airway condition of sEA-affected horses. The objectives were to determine the clinical, cytological and cytokine respiratory responses of both sEA and control (CTL) horses experimentally exposed to steamed or dry hay. Results A cohort of 6 sEA horses and 6 CTL horses was involved in this field study. On day 0, both groups were fed with steamed hay for 5 consecutive days, followed by a wash-out period of 26 days prior to be fed with dry hay for 5 consecutive days. Investigations performed 2 days prior to and 5 days after each challenge included clinical score, tracheal mucus accumulation, and bronchoalveolar lavage fluid (BALF) cytology and cytokine mRNA expression. Feeding steamed hay significantly decreased its mould content (P
Databáze: OpenAIRE
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