Effects of zinc gluconate and nedocromil sodium on performance deficits produced by the common cold
| Autor: | D. A. J. Tyrrell, W. Al-Nakib, R. B. M. Wenham, Andrew Paul Smith, P.G. Higgins, I. Barrow |
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| Rok vydání: | 2012 |
| Předmět: |
Pharmacology
Drug Trigeminal stimulation media_common.quotation_subject 05 social sciences Performance impairment chemistry.chemical_element 050109 social psychology Common cold Zinc medicine.disease 050105 experimental psychology Psychiatry and Mental health chemistry medicine 0501 psychology and cognitive sciences Pharmacology (medical) Clinical efficacy Nedocromil Sodium Mode of action media_common |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 0269-8811 |
| Popis: | Two studies are reported on the effects of drugs on the performance impairments induced by experimentally- produced colds. The first study examined the effects of zinc gluconate on choice reaction time, and showed that the zinc removed the cold-induced performance impairment. The second experiment used nedocromil sodium and, again, the drug was effective in reducing the drop in performance observed in volunteers with colds. While the precise mode of action of these compounds is unclear it is speculated that one mechanism involves changes in trigeminal stimulation, and this could be responsible for both the clinical efficacy and CNS effects of these drugs. |
| Databáze: | OpenAIRE |
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