Popis: |
Background: Primary leptomeningeal melanoma is an extremely rare type of intracranial melanoma. It cannot be reliably distinguished from metastatic melanoma on neuroimaging and histopathological characteristics alone; its diagnosis is established only after exclusion of secondary metastatic disease from a cutaneous, mucosal or retinal primary [1, 2]. Prognosis is poor, partly due to its high rate of misdiagnosis. Case presentation: We report a case of a Primary Meningeal Melanoma of the skull base with Melanomatosis, in 31 years old man, mimicking clinical and radiological features of meningioma and whose delayed treatment has worsened the prognosis. Conclusion: Through this case, we highlight the diagnostic difficulties and we discuss the histopathological differential diagnoses especially with other pigmented lesions of Central nervous system (CNS). |