Impact of Young Age on the Prognosis for Oral Cancer: A Population-Based Study in Taiwan
| Autor: | Ching-Chih Lee, Chun-Ming Chang, Yu-Chieh Su, Li-Fu Chen, Ting-Shou Chang, Pesus Chou, Hsu-Chieh Ho |
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| Rok vydání: | 2013 |
| Předmět: |
Adult
medicine.medical_specialty Taiwan lcsh:Medicine Cohort Studies Internal medicine medicine Humans lcsh:Science Survival rate Survival analysis Aged Proportional Hazards Models Mouth neoplasm Multidisciplinary business.industry Proportional hazards model lcsh:R Hazard ratio Age Factors Cancer Middle Aged Prognosis medicine.disease Survival Analysis Confidence interval Surgery Survival Rate Propensity score matching Mouth Neoplasms lcsh:Q business Research Article |
| Zdroj: | PLoS ONE, Vol 8, Iss 9, p e75855 (2013) PLoS ONE |
| ISSN: | 1932-6203 |
| DOI: | 10.1371/journal.pone.0075855 |
| Popis: | BACKGROUND: Oral cancer leads to a considerable use of health care resources. Wide resection of the tumor and reconstruction with a pedicle flap/ free flap is widely used. This study was conducted to investigate if young age at the time of diagnosis of oral cancer requiring this treatment confers a worse prognosis. METHODS: A total of 2339 patients who underwent resections for oral cancer from 2004 to 2005 were identified from The Taiwan National Health Insurance Research Database. Survival analysis, Cox proportional regression model, propensity scores, and sensitivity test were used to evaluate the association between 5-year survival rates and age. RESULTS: In the Cox proportional regression model, the older age group (>65 years) had the worst survival rate (hazard ratio [HR], 1.80; 95% confidence interval [CI], 1.45-2.22; P65 years), compared to those with younger age ( |
| Databáze: | OpenAIRE |
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