Ca2+ sensor-mediated ROS scavenging suppresses rice immunity and is exploited by a fungal effector
| Autor: | Yiwen Deng, Guo-Liang Wang, Guiquan Zhang, Jin Chen, Xiangyu Gong, Jiyun Liu, Didier Tharreau, Shenghan Xie, Huizhong Chang, Jiaxing Yue, Yang He, Keran Zhai, Xin Yin, Jianlong Xu, Yue Wu, Bingxiao Yan, Yifeng Huang, Xiangbin Zhong, Ertao Wang, Mingjun Gao, Zuhua He, Xiaoyuan Li, Weibing Yang |
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| Přispěvatelé: | CAS Center for Excellence in Molecular Plant Sciences (CEMPS), Chinese Academy of Sciences [Beijing] (CAS), ShanghaiTech University [Shanghai], Sun Yat-sen University Cancer Center (SYSUCC), Sun Yat-Sen University [Guangzhou] (SYSU), Chinese Academy of Agricultural Sciences (CAAS), South China Agricultural University (SCAU), Plant Health Institute of Montpellier (UMR PHIM), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD)-Université de Montpellier (UM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro - Montpellier SupAgro, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Département Systèmes Biologiques (Cirad-BIOS), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad), Ohio State University [Columbus] (OSU), National Natural Science Foundation of China (32088102, 31930090, and 31720103913 and 31801718 .), the Chinese Academy of Sciences Strategic Priority Research Program (XDB27040201 and XDB27030107 .), the National Key Research and Development Program of China (2016YFD0100600), the Sino-German Center for Research Promotion (M-0275), the Science and Technology Commission of ShanghaiMunicipality (19391900300), China Postdoctoral Science Foundation (2019M650036, 2018M640425)., the National Postdoctoral Program for Innovative Talents (BX201700269) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
pyriculariose du riz
F60 - Physiologie et biochimie végétale Homéostasie Plant Immunity Virulence Oryza sativa Plant disease resistance Xanthomonas oryzae General Biochemistry Genetics and Molecular Biology Immune system Maladie des plantes Immunity Effecteur moléculaire H20 - Maladies des plantes chemistry.chemical_classification Reactive oxygen species biology Effector Rhizoctonia solani food and beverages Résistance aux maladies Catalase dérivé réactif de l'oxygène Cell biology Physiologie végétale [SDV.BV.PEP]Life Sciences [q-bio]/Vegetal Biology/Phytopathology and phytopharmacy chemistry biology.protein Immunité |
| Zdroj: | Cell Cell, 2021, 184 (21), pp.5391-5404.e17. ⟨10.1016/j.cell.2021.09.009⟩ |
| ISSN: | 0092-8674 1097-4172 |
| DOI: | 10.1016/j.cell.2021.09.009⟩ |
| Popis: | International audience; Plant immunity is activated upon pathogen perception and often affects growth and yield when it is constitutively active. How plants fine-tune immune homeostasis in their natural habitats remains elusive. Here, we discover a conserved immune suppression network in cereals that orchestrates immune homeostasis, centering on a Ca2+-sensor, RESISTANCE OF RICE TO DISEASES1 (ROD1). ROD1 promotes reactive oxygen species (ROS) scavenging by stimulating catalase activity, and its protein stability is regulated by ubiquitination. ROD1 disruption confers resistance to multiple pathogens, whereas a natural ROD1 allele prevalent in indica rice with agroecology-specific distribution enhances resistance without yield penalty. The fungal effector AvrPiz-t structurally mimics ROD1 and activates the same ROS-scavenging cascade to suppress host immunity and promote virulence. We thus reveal a molecular framework adopted by both host and pathogen that integrates Ca2+ sensing and ROS homeostasis to suppress plant immunity, suggesting a principle for breeding disease-resistant, high-yield crops. |
| Databáze: | OpenAIRE |
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