Prisms to Shift Pain Away: Pathophysiological and Therapeutic Exploration of CRPS with Prism Adaptation
| Autor: | Eric Chabanat, Laure Christophe, Patrice Revol, Yves Rossetti, Pierre Volckmann, Ludovic Delporte, Sophie Jacquin-Courtois |
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| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Psychotherapist Article Subject genetic structures media_common.quotation_subject 050105 experimental psychology Neglect lcsh:RC321-571 03 medical and health sciences 0302 clinical medicine Quality of life (healthcare) Physical medicine and rehabilitation Intervention (counseling) medicine 0501 psychology and cognitive sciences Body Representation lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry media_common Proprioception 05 social sciences medicine.disease Complex regional pain syndrome Neurology Extinction (neurology) Neurology (clinical) Psychology Prism adaptation 030217 neurology & neurosurgery Research Article |
| Zdroj: | Neural Plasticity Neural Plasticity, Vol 2016 (2016) |
| ISSN: | 1687-5443 |
| Popis: | Complex Regional Pain Syndrome (CRPS) is an invalidating chronic condition subsequent to peripheral lesions. There is growing consensus for a central contribution to CRPS. However, the nature of this central body representation disorder is increasingly debated. Although it has been repeatedly argued that CRPS results in motor neglect of the affected side, visual egocentric reference frame was found to be deviated toward the pain, that is, neglect of the healthy side. Accordingly, prism adaptation has been successfully used to normalize this deviation. This study aimed at clarifying whether 7 CRPS patients exhibited neglect as well as exploring the pathophysiological mechanisms of this manifestation and of the therapeutic effects of prism adaptation. Pain and quality of life, egocentric reference frames (visual and proprioceptive straight-ahead), and neglect tests (line bisection, kinematic analyses of motor neglect and motor extinction) were repeatedly assessed prior to, during, and following a one-week intense prism adaptation intervention. First, our results provide no support for visual and motor neglect in CRPS. Second, reference frames for body representations were not systematically deviated. Third, intensive prism adaptation intervention durably ameliorated pain and quality of life. As for spatial neglect, understanding the therapeutic effects of prism adaptation deserves further investigations. |
| Databáze: | OpenAIRE |
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