Hemiplegic Migraine in Glut1 Deficiency Syndrome and Paroxysmal Dyskinesia at Ketogenic Diet Induction: Case Report and Literature Review
| Autor: | Anja Heinze, Andreas Merkenschlager, Rami Abou Jamra, Janina Gburek-Augustat |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Pediatrics medicine.medical_specialty endocrine system Deficiency syndrome Paroxysmal nonkinesigenic dyskinesia medicine.medical_treatment Central nervous system 030105 genetics & heredity 03 medical and health sciences 0302 clinical medicine medicine Case Series with Literature Review business.industry nutritional and metabolic diseases Paroxysmal dyskinesia medicine.disease Discontinuation carbohydrates (lipids) medicine.anatomical_structure Neurology Hemiplegic migraine Neurology (clinical) Complication business 030217 neurology & neurosurgery hormones hormone substitutes and hormone antagonists Ketogenic diet |
| Zdroj: | Mov Disord Clin Pract |
| Popis: | Background A rare symptom of Glut1 deficiency syndrome (Glut1 DS) is hemiplegic migraine (HM). Case We report a patient with Glut1 DS with a mild phenotype. His leading symptom was HM. As an unusual complication of the initiation of a ketogenic diet (KD), our patient developed paroxysmal nonkinesigenic dyskinesia. Paroxysmal dyskinesia occurred first and exclusively at the initiation of KD. Literature review There are a few case reports for HM in Glut1 DS. All patients had additional neurological symptoms. Regarding central nervous system symptoms such as paroxysmal dyskinesia triggered by KD, we found only 1 other case report. Discussion HM is part of the symptom complex of Glut1 DS and can be effectively treated by KD. Paroxysmal dyskinesia trigged by the initiation of KD should not lead to the discontinuation of the diet in Glut1 DS. |
| Databáze: | OpenAIRE |
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