Prognostic Factors in Patients with Differentiated Thyroid Cancers Metastatic to the Cervical Spine
| Autor: | Linda X. Yin, Eric J. Moore, Cassandra L. Puccinelli, Daniel L. Price, Kathryn M. Van Abel, Jan L. Kasperbauer, Jeffrey R. Janus, Mabel Ryder |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty 030209 endocrinology & metabolism Kaplan-Meier Estimate Metastasis 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine medicine Humans Orthopedic Procedures Thyroid Neoplasms Risk factor Thyroid cancer Survival analysis Aged Retrospective Studies Neck pain Neck Pain Spinal Neoplasms business.industry Hazard ratio Retrospective cohort study Middle Aged Prognosis medicine.disease Confidence interval Treatment Outcome Otorhinolaryngology 030220 oncology & carcinogenesis Cervical Vertebrae Female medicine.symptom business Follow-Up Studies |
| Zdroj: | The Laryngoscope. 131 |
| ISSN: | 1531-4995 0023-852X |
| Popis: | OBJECTIVES The spine is the most common site of bone metastases in differentiated thyroid cancer (DTC). The role of surgery in the management of cervical spine (C-spine) metastases (CSpM) has not been adequately explored. METHODS This is a retrospective cohort study at a tertiary referral center from 2002 to 2018. Inclusion criteria were pathologic diagnosis of DTC and imaging/pathologic diagnosis of CSpM. Statistical analysis utilized t tests for continuous variables and χ2 tests for categorical variables. Survival analysis was conducted using Kaplan-Meier curves with univariate and multivariate Cox regressions. RESULTS Fifty patients with DTC and CSpM were identified. Of those, 16 underwent surgical resection of the C-spine, whereas 34 did not. The most common presenting symptom was neck pain (N = 37, 74%). Patients in the surgery group were more likely to report a subjective improvement of symptoms (P |
| Databáze: | OpenAIRE |
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