Coronary artery disease affecting the atrial branches is an independent determinant of atrial fibrillation after myocardial infarction
Autor: | Hany S. Abed, Walter P. Abhayaratna, Han S. Lim, Muayad Alasady, Matthew I. Worthley, Darryl P. Leong, Sue Mattchoss, Prashanthan Sanders, Derek P. Chew, Kurt C. Roberts-Thomson, Anthony G. Brooks |
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Rok vydání: | 2011 |
Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Myocardial Infarction Coronary Artery Disease Coronary Angiography Ventricular Function Left Coronary artery disease Electrocardiography Risk Factors Physiology (medical) Internal medicine Atrial Fibrillation South Australia medicine Humans Myocardial infarction Aged Retrospective Studies Ejection fraction medicine.diagnostic_test business.industry Incidence Percutaneous coronary intervention Atrial fibrillation medicine.disease Survival Rate Echocardiography Heart failure Cardiology Myocardial infarction complications Female Cardiology and Cardiovascular Medicine business Follow-Up Studies |
Zdroj: | Heart Rhythm. 8:955-960 |
ISSN: | 1547-5271 |
Popis: | During acute myocardial infarction (MI), the incidence of atrial fibrillation (AF) is 6% to 22%, and its occurrence in this setting is associated with increased short- and long-term morbidity and mortality.The purpose of this case control study was evaluate the characteristics associated with the development of new-onset AF.Of 2,460 consecutive patients with acute MI, 149 (6%) were identified as having AF within 7 days of MI. After excluding patients with prior AF, previously documented heart failure, reduced left ventricular (LV) ejection fraction, valvular heart disease, LV hypertrophy, AF after coronary artery bypass grafting, or pericarditis; we identified 42 AF patients in whom coronary anatomy was assessed by invasive angiography and cardiac structure and function was evaluated using transthoracic echocardiography. Another 42 patients from the same cohort with MI but no AF matched for age, gender, and LV ejection fraction were studied as controls.AF patients were more likely to present with an inferior MI (P = .002) but less likely to present with ST-segment elevation MI (P = .02). Univariate associations with AF included indexed left atrial volume (P.001), LV filling pressure (E/e'; P = .001), right atrial branch disease (P.001), left atrial branch disease (P = .009), sinoatrial branch disease (P.001), left main stem disease (P = .02), and time from onset of symptoms to coronary intervention (P = .002). In multivariable analysis, right and left coronary artery atrial branch disease (P = .02) were predictors of AF post-MI.Coronary artery disease affecting the atrial branches is an independent predictor for the development of AF after MI. |
Databáze: | OpenAIRE |
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