Predictors of symptomatic oral lichen planus
| Autor: | Jenene Noll, Michael D. Carpenter, Anna Osipoff, Michael T. Brennan, J. Amadeo Valdez, Martin Gormsen |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Asymptomatic Pathology and Forensic Medicine Tongue Diseases Lesion 03 medical and health sciences 0302 clinical medicine stomatognathic system Tongue Internal medicine Medicine Humans Radiology Nuclear Medicine and imaging Dentistry (miscellaneous) Retrospective Studies business.industry Retrospective cohort study 030206 dentistry medicine.disease stomatognathic diseases medicine.anatomical_structure Tongue disease Mycoses 030220 oncology & carcinogenesis Cohort Surgery Oral lichen planus Female Steroids Oral Surgery medicine.symptom business Topical steroid Lichen Planus Oral |
| Zdroj: | Oral surgery, oral medicine, oral pathology and oral radiology. 129(5) |
| ISSN: | 2212-4411 |
| Popis: | Objective The aim of this study was to determine the prevalence and the factors associated with symptomatic oral lichen planus (OLP). Study Design Patients with OLP seen for an initial visit were assessed retrospectively. Initial visit data included demographic characteristics; social, medical, and OLP treatment histories; medications; chief complaints, 0 to 10 pain level; OLP duration and symptoms; OLP type and location; total OLP lesion size (mm2); total ulcer size (mm2); and fungal infection and its management. Follow-up data included 0 to 10 pain level and total lesion and ulcer sizes. Results We assessed 205 patients: 154 (75%) were women, and the mean (standard deviation [SD]) age was 62.5 (11.5) years. The mean (SD) current pain level was 1.6 (2.2) at the initial visit. A total of 125 patients (61%) were classified as symptomatic, including 85 (41%) patients reporting a pain level of 1 or greater and another 40 patients (20%) who had symptoms not described as pain at the initial visit. The following increased the odds of OLP symptoms at the initial visit: tongue location (× 2.3), erosive/erythematous type (× 2.3), female sex (× 2.9), topical steroid use before initial visit (× 2.1), and number of medical conditions (× 1.2). Conclusions Most patients with OLP in the present cohort were symptomatic at the initial visit, with location, type, sex, steroid use and medical conditions being predictors of symptomatic OLP. Despite improvement in OLP symptoms in most patients over time, 25% of patients who are asymptomatic at the initial visit present with symptomatic OLP at a future visit. |
| Databáze: | OpenAIRE |
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