Lockdown measures and relative changes in the age-specific incidence of SARS-CoV-2 in Spain
| Autor: | Martínez de Salazar, Pablo, Gómez-Barroso, D., Pampaka, D., Gil, J. M., Peñalver, B., Fernández-Escobar, C., Lipsitch, M., Larrauri, A., Goldstein, E., Hernán, M. A., Universitat Autònoma de Barcelona |
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| Přispěvatelé: | Fundación Ramón Areces, National Institute of General Medical Sciences (United States), Morris-Singer Fund, Andrew and Corey Morris-Singer Foundation, NIH - National Institute of General Medical Sciences (NIGMS) (Estados Unidos) |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
0301 basic medicine Adolescent Epidemiology Relative incidence Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Pneumonia Viral Article lockdown Betacoronavirus Young Adult 03 medical and health sciences Age Distribution 0302 clinical medicine Age groups Lockdown Humans Medicine Cumulative incidence 030212 general & internal medicine Symptom onset Young adult Pandemics Age specific incidence Aged Original Paper Pneumonia Viral / epidemiology Spain / epidemiology business.industry SARS-CoV-2 Coronavirus Infections / epidemiology Incidence Incidence (epidemiology) COVID-19 Middle Aged 030104 developmental biology Infectious Diseases Social Isolation Younger adults Spain Quarantine High incidence Outbreak control Coronavirus Infections business Demography |
| Zdroj: | Dipòsit Digital de Documents de la UAB Universitat Autònoma de Barcelona Epidemiology and Infection Repisalud Instituto de Salud Carlos III (ISCIII) medRxiv EPIDEMIOLOGY AND INFECTION r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau instname |
| ISSN: | 0950-2688 |
| Popis: | During the first months of the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) epidemic in 2020, Spain implemented an initial lockdown period on 15 March followed by a strengthened lockdown period on 30 March when only essential workers continued to commute to work. However, little is known about the epidemic dynamics in different age groups during these periods.We used the daily number of coronavirus 2019 cases (by date of symptom onset) reported to the National Epidemiological Surveillance Network among individuals aged 15–19 years through 65–69 years. For each age groupg, we computed the proportion PrE(g) of individuals in age groupgamong all reported cases aged 15–69 years during the pre-lockdown period (1−10 March 2020) and the corresponding proportion PrL(g) during two lockdown periods (initial: 25 March−3 April; strengthened: 8–17 April 2020). For each lockdown period, we computed the proportion ratios PR(g) = PrL(g)/PrE(g). For each pair of age groupsg1,g2, PR(g1)>PR(g2) implies a relative increase in the incidence of detected SARS-CoV-2 infection in the age groupg1compared withg2for the lockdown periodvs.the pre-lockdown period.For the initial lockdown period, the highest PR values were in age groups 50–54 years (PR = 1.21; 95% CI: 1.12,1.30) and 55–59 years (PR = 1.19; 1.11,1.27). For the second lockdown period, the highest PR values were in age groups 15–19 years (PR = 1.26; 0.95,1.68) and 50–54 years (PR = 1.20; 1.09,1.31).Our results suggest that different outbreak control measures led to different changes in the relative incidence by age group. During the initial lockdown period, when non-essential work was allowed, individuals aged 40–64 years, particularly those aged 50–59 years, had a higher relative incidence compared with the pre-lockdown period. Younger adults/older adolescents had an increased relative incidence during the later, strengthened lockdown. The role of different age groups during the epidemic should be considered when implementing future mitigation efforts. |
| Databáze: | OpenAIRE |
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