A Unique Case of Allogeneic Fat Grafting Between Brothers
| Autor: | Deepak Narayan, Stephanie Kwei, Richard L. Edelson, Brandon J. Sumpio, Samuel Kim |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
business.industry
medicine.medical_treatment Case Report Disease Hematopoietic stem cell transplantation 030230 surgery medicine.disease Lymphoma Malignant transformation 03 medical and health sciences Haematopoiesis surgical procedures operative 0302 clinical medicine hemic and lymphatic diseases 030220 oncology & carcinogenesis Immunology Minor histocompatibility antigen medicine Fat grafting ComputingMethodologies_DOCUMENTANDTEXTPROCESSING Surgery Stem cell business |
| Zdroj: | Plastic and Reconstructive Surgery Global Open |
| ISSN: | 2169-7574 |
| Popis: | Supplemental Digital Content is available in the text. Summary: We present a case of a 65-year-old man with cutaneous T-cell lymphoma treated with radiation therapy and an allogeneic hematopoietic stem cell transplant from his human leukocyte antigen-matched brother. Engraftment was successful, but the patient went on to develop painful, radiation-induced ulcers. The ulcers were fat-allografted using liposuctioned fat from his brother because of the patient’s unique chimeric state. Postprocedure follow-up revealed epithelialization of the ulcer sites and significant improvement in neuropathic pain. Our unique case study supports the use of fat grafting for its restorative purposes and for its ability to alleviate chronic neuropathic pain. Additionally, it appears that our case provides a basis of a general approach to the treatment of radiation-induced ulcers in chimeric patients with lymphoid malignancies. |
| Databáze: | OpenAIRE |
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