A case of Aspergillus nidulans causing white granule mycetoma

Autor: Puneet Bhatt, Naveen Grover, A.K. Sahni, S. Prasanna
Rok vydání: 2016
Předmět:
Zdroj: Medical Journal Armed Forces India. 72:88-90
ISSN: 0377-1237
DOI: 10.1016/j.mjafi.2014.11.003
Popis: Mycetoma is a frequent fungal infection encountered in dermatological practice. The clinical picture is slowly progressive, causing chronic granulomatous infection of skin and subcutaneous tissues with involvement of underlying fasciae and bones usually affecting the extremities.1 This disease is defined by the triad of tumefaction of affected tissue, formation of multiple draining sinuses and presence of oozing granules.1 In most cases it is caused by two groups of organisms – fungi (eumycetoma) and bacteria (actinomycetoma and botryomycosis). The eumycetoma is classified into black granule eumycetoma and white granule eumycetoma. The white granule mycetoma is caused by more than 10 species of fungi such as Acremonium species, Pseudoallescheria boydii, Aspergillus nidulans, Aspergillus flavus, Fusarium species and Scedosporium apiospermum. The black granule mycetoma is caused by Madurella mycetomatis, Madurella grisea, Exophiala jeanselmei, Curvularia geniculata.1, 2 Mycetoma is worldwide in distribution, mostly seen in rural areas and is mainly occupation related. The prevalence of mycetoma varies widely being more frequent in hot, humid, tropical and sub-tropical areas. Mycetoma is endemic in Africa, Sudan, Senegal, southern and northern parts of India. As there is a huge difference between treatment of mycetoma due to fungal and bacterial cause, identification of the etiological agent plays a major role in the management.2, 3, 4, 5 White granule mycetoma is very rare and has been reported rarely worldwide as well as in India. Till now, only a few cases of white granule mycetoma caused by A. nidulans have been reported. The objective of this case report was to present a rare case of white granule mycetoma caused by A. nidulans in a diabetic adult individual residing in Pune, Maharashtra.
Databáze: OpenAIRE