Synthesis of lipophosphoramidyl-cyclodextrins and their supramolecular properties
| Autor: | Paul-Alain Jaffrès, Véronique Bonnet, Cédric Gervaise, Florence Djedaïni-Pilard, Catherine Sarazin, Olivier Wattraint, Frédéric Aubry |
|---|---|
| Přispěvatelé: | Génie Enzymatique et Cellulaire (GEC), Université de Technologie de Compiègne (UTC)-Université de Picardie Jules Verne (UPJV)-Centre National de la Recherche Scientifique (CNRS), Laboratoire des Glucides (LG), Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Picardie Jules Verne (UPJV), Chimie, Electrochimie Moléculaires et Chimie Analytique (CEMCA), Institut Brestois Santé Agro Matière (IBSAM), Université de Brest (UBO)-Université de Brest (UBO)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC), David, Chantal, Université de Picardie Jules Verne (UPJV)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS) |
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Spectrometry
Mass Electrospray Ionization Atherton–Todd reaction Magnetic Resonance Spectroscopy Light Dispersity Supramolecular chemistry Nanoparticle Phosphate 010402 general chemistry 01 natural sciences Biochemistry Dynamic light scattering Polymer chemistry Amphiphile Organic chemistry Scattering Radiation Surface Tension [CHIM]Chemical Sciences Phosphoric Acids Amphiphilic cyclodextrin chemistry.chemical_classification Cyclodextrins Cyclodextrin Aqueous medium 010405 organic chemistry [CHIM.ORGA]Chemical Sciences/Organic chemistry Scopolamine Derivatives General Medicine Amides Lipids 0104 chemical sciences chemistry Calibration Nanoparticles |
| Zdroj: | Biochimie Biochimie, Elsevier, 2012, 94 (1), pp.66-74. ⟨10.1016/j.biochi.2011.09.005⟩ Biochimie, Elsevier, 2012, 94, pp.66-74 |
| ISSN: | 0300-9084 |
| Popis: | International audience; The synthesis of lipophosphoramidyl-β-CD was obtained by an Atherton-Todd (AT) reaction that involved dioleylphosphite and either functionalized permethylated or native β-cyclodextrin. This AT reaction that produced dioleylphosphoramide by making use of the amino group grafted on cyclodextrin, was optimized for these cyclic oligosaccharides. These new amphiphilic compounds were fully characterized, and their self-assembling properties were investigated: the mean size diameter and polydispersity measured by Dynamic Light Scattering (DLS) were affected by the nature of the aqueous media and the temperature of storage. The encapsulation properties of these nanoparticles have been evaluated using carboxyfluorescein and scopolamine derivatives as model of guests. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect