A Wideband Microwave Exposure Setup for Suspended Cells Cultures: Numerical and Experimental EM Characterization

Autor: Alice Collin, Caterina Merla, Philippe Lévêque, Anne Perrin, Delia Arnaud-Cormos
Přispěvatelé: BIO-INGENIERIE (XLIM-BIO-INGENIERIE), XLIM (XLIM), Université de Limoges (UNILIM)-Centre National de la Recherche Scientifique (CNRS)-Université de Limoges (UNILIM)-Centre National de la Recherche Scientifique (CNRS), Radiobiology Department of the Health Service Research Center for Defense (IRBA-CRSSA), Institut de Recherche Biomédicale des Armées (IRBA-CRSSA), Institut Universitaire de France (IUF), Ministère de l'Education nationale, de l’Enseignement supérieur et de la Recherche (M.E.N.E.S.R.)
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: IEEE Antennas and Wireless Propagation Letters
IEEE Antennas and Wireless Propagation Letters, Institute of Electrical and Electronics Engineers, 2016, 15, ⟨10.1109/LAWP.2015.2440560⟩
ISSN: 1536-1225
Popis: An in vitro exposure setup developed to expose suspended cells in Petri dishes on a large frequency band up to a few gigahertz was studied. This system was based on far-field exposure with a horn antenna in an anechoic chamber. A specific incubator was designed with a water-cooling system for constant temperature inside the setup. Four exposed Petri dishes presented a similar specific absorption rate (SAR) distribution with a whole-volume SAR of $0.56 \pm 0.40~\hbox{W/kg/W}_{\rm inc}$ at 2.45 GHz. The incubator was equipped with a stirring mechanism allowing an homogenous distribution of temperature in the biological solution. The SAR was assessed over the 1.5–3 GHz frequency range. Using the temperature control and stirring, an increase of 0.4 $^\circ {\rm C}$ in temperature was observed after 2 h exposure at 2.45 GHz, 22 W incident power. This dosimetric study demonstrated the ability of this system to expose cells in suspension at different frequencies in a controlled environment .
Databáze: OpenAIRE