Hemolysis and Heat Generation in Six Different Types of Centrifugal Blood Pumps
| Autor: | Yuzo Baba, Toru Masuzawa, Masanobu Watari, Hisateru Takano, Yoshiyuki Taenaka, Eisuke Tatsumi, H. Anai, K. Araki, Young Hwan Park, Yoshinari Wakisaka, Kazuhiro Eya, Koichi Toda, Takeshi Nakatani, Haruhiko Akagi |
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| Rok vydání: | 1995 |
| Předmět: |
Energy loss
Hot Temperature Chemistry Goats Biomedical Engineering Medicine (miscellaneous) Thermodynamics Centrifugation Bioengineering General Medicine Centrifugal pump Thermal conduction medicine.disease Hemolysis Volumetric flow rate Biomaterials Pressure head Heat generation medicine Animals Composite material Infusion Pumps |
| Zdroj: | Artificial Organs. 19:928-932 |
| ISSN: | 1525-1594 0160-564X |
| Popis: | What the most causative factor affecting hemolysis is still controversial. To resolve this problem, we investigated the relationship between hemolysis and heat generation in six types of centrifugal blood pumps (Bio-Pump, Delphin, Capiox, Nikkiso, Isoflow, and Toyobo). The analyzed parameters were index of hemolysis in fresh goat blood, pumping performance, and heat generation in a thermally isolated mock circuit. These parameters were analyzed at a flow rate of 5 L/min by changing the pressure head (100 mm Hg and 500 mm Hg). At 500 mm Hg of pressure head, the Bio-Pump needed the highest rotation number and showed the highest hemolytic rate and heat generation. The index of hemolysis is well correlated to heat generation (r2 = 0.721). Heat may originate from the motor by conduction, hydraulic energy loss, and mechanical friction between the shaft and seal. We strongly suspect that hemolysis was caused by a factor such as mechanical friction which generates heat locally. |
| Databáze: | OpenAIRE |
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