Acellular Scaffolds as Innovative Biomaterial Platforms for the Management of Diabetic Wounds
| Autor: | C Kalaivani, Vyshnavi Tallapaneni, Sachin Kumar Singh, Lavanya Mude, Veera Venkata Satyanarayana Reddy Karri, Divya Pamu |
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| Rok vydání: | 2021 |
| Předmět: |
0303 health sciences
medicine.medical_specialty Wound Healing business.industry 0206 medical engineering Biomedical Engineering Medicine (miscellaneous) Biocompatible Materials 02 engineering and technology Review Article 020601 biomedical engineering Diabetic wound 03 medical and health sciences Recovery period medicine Diabetes Mellitus Humans Acellular scaffold Intensive care medicine business Wound healing 030304 developmental biology |
| Zdroj: | Tissue Eng Regen Med |
| ISSN: | 2212-5469 |
| Popis: | Diabetic wound (DW) is one of the leading complications of patients having a long history of uncontrolled diabetes. Moreover, it also imposes an economic burden on people suffering from wounds to manage the treatment. The major impending factors in the treatment of DW are infection, prolonged inflammation and decreased oxygen levels. Since these non-healing wounds are associated with an extended recovery period, the existing therapies provide treatment for a limited period only. The areas covered in this review are general sequential events of wound healing along with DW's pathophysiology, the origin of DW and success, as well as limitations of existing therapies. This systematic review's significant aspect is to highlight the fabrication, characterization and applications of various acellular scaffolds used to heal DW. In addition to that, cellular scaffolds are also described to a limited extent. |
| Databáze: | OpenAIRE |
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