Characterization of anomalous movements of spherical living cells on a silicon dioxide glassy substrate
| Autor: | Sei Young Lee, Jongsang Son, Sang Woo Lee, Seungyeop Choi, Gyudo Lee, Youngho Kim, Myeonggu Son, Young-Ro Yoon, Dae Sung Yoon |
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| Rok vydání: | 2014 |
| Předmět: |
Fluid Flow and Transfer Processes
Mesoscopic physics Uniform distribution (continuous) Materials science Anomalous diffusion Stochastic process Silicon dioxide Biomedical Engineering Substrate (electronics) Weak interaction Condensed Matter Physics Random walk Crystallography chemistry.chemical_compound Colloid and Surface Chemistry chemistry Chemical physics General Materials Science Regular Articles |
| Zdroj: | Biomicrofluidics. 9(1) |
| ISSN: | 1932-1058 |
| Popis: | The random walk of spherical living cells on a silicon dioxide glassy substrate was studied experimentally and numerically. This random walk trajectory exhibited erratic dancing, which seemingly obeyed anomalous diffusion (i.e., Levy-like walk) rather than normal diffusion. Moreover, the angular distribution (−π to π) of the cells' trajectory followed a “U-shaped pattern” in comparison to the uniform distribution seen in the movements of negatively charged polystyrene microspheres. These effects could be attributable to the homeostasis-driven structural resilient character of cells and physical interactions derived from temporarily retained nonspecific binding due to weak forces between the cells and substrates. Our results provide new insights into the stochastic behavior of mesoscopic biological particles with respect to structural properties and physical interactions. |
| Databáze: | OpenAIRE |
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