HIV seroconversion interval and demographic characteristics: no evidence of selection bias
Autor: | Jacques Ritter, Dominique Peyramond, Muriel Dhenain, Jean-Louis Touraine, Christian Chidiac, Christian Trepo, Philippe Vanhems, Jacques Fabry, Robert Allard |
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Rok vydání: | 2001 |
Předmět: |
Adult
Male medicine.medical_specialty Time Factors Multivariate analysis media_common.quotation_subject Dermatology Acquired immunodeficiency syndrome (AIDS) Internal medicine HIV Seropositivity Epidemiology medicine Humans Prospective Studies Seroconversion Sida Prospective cohort study GeneralLiterature_REFERENCE(e.g. dictionaries encyclopedias glossaries) Selection Bias media_common Selection bias biology business.industry virus diseases Original Articles Middle Aged biology.organism_classification medicine.disease Infectious Diseases Immunology Disease Progression Linear Models Female France Viral disease business |
Zdroj: | Sexually Transmitted Infections. 77:446-448 |
ISSN: | 1368-4973 |
Popis: | Objectives: To determine if the interval between the last negative and the first positive HIV test is associated with demographic characteristics of HIV seroconverters. Methods: A prospective cohort of patients with HIV seroconversion enrolled in the Lyons HIV hospital database was analysed. Comparisons of demographic characteristics were performed after stratification on the duration of the interval between the last HIV negative screening test and the first HIV positive screening test, which ranged from 1 day to 24 months. Linear regression methods were used to identify the covariates associated with a negative HIV antibody test followed by a positive test. Results: Age (p=0.54), sex (p=0.78), heterosexual route of infection (p=0.78), other route (p=0.40) compared with homosexual route, and estimated year of HIV infection (p value ranged from 0.84 to 0.95) were not associated with a shorter seroconversion interval after multivariate analyses. The presence of an acute HIV illness was the only predictor of a short seroconversion interval (p=0.006) with a reduction of 84 days of the interval when it was reported. Conclusions: No selection bias for demographic characteristics of HIV seroconverters seems associated with the length of the seroconversion interval, at least for intervals ≤24 months. |
Databáze: | OpenAIRE |
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