Addressing tuberculosis control in fragile states: Urban DOTS experience in Kabul, Afghanistan, 2009-2015

Autor: L. Manzoor, N. Ikram, Mohammad Khaled Seddiq, M. Sayedi, M. Rashidi, G. Qader, A. Hamim, Pedro Suarez
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Bacterial Diseases
Male
Health Screening
Urban Population
Antitubercular Agents
lcsh:Medicine
Geographical Locations
0302 clinical medicine
Medicine and Health Sciences
Public and Occupational Health
030212 general & internal medicine
lcsh:Science
Child
Geographic Areas
education.field_of_study
Multidisciplinary
Geography
Drugs
Infectious Diseases
Tuberculosis Diagnosis and Management
Female
National average
Tuberculosis control
International development
Research Article
Urban Areas
medicine.medical_specialty
Tuberculosis
Asia
Death Rates
030231 tropical medicine
Population
03 medical and health sciences
Diagnostic Medicine
Environmental health
medicine
Isoniazid
Humans
education
Demography
Pharmacology
business.industry
Public health
lcsh:R
Afghanistan
Private sector
medicine.disease
Tropical Diseases
Directly Observed Therapy
People and Places
Earth Sciences
Public Health Practice
lcsh:Q
Contact Tracing
business
Contact tracing
Zdroj: PLoS ONE
PLoS ONE, Vol 12, Iss 5, p e0178053 (2017)
ISSN: 1932-6203
Popis: Tuberculosis (TB) is a major public health problem in Afghanistan, but experience in implementing effective strategies to prevent and control TB in urban areas and conflict zones is limited. This study shares programmatic experience in implementing DOTS in the large city of Kabul. We analyzed data from the 2009-2015 reports of the National TB Program (NTP) for Kabul City and calculated treatment outcomes and progress in case notification using rates, ratios, and confidence interval. Urban DOTS was implemented by the NTP in partnership with United States Agency for International Development (USAID)-funded TB projects, the World Health Organization (WHO), and the private sector. Between 2009 and 2015, the number of DOTS-providing centers in Kabul increased from 22 to 85. In total, 24,619 TB patients were enrolled in TB treatment during this period. The case notification rate for all forms of TB increased from 59 per 100,000 population to 125 per 100,000. The case notification rate per 100,000 population for sputum-smear-positive TB increased from 25 to 33. The treatment success rate for all forms of TB increased from 31% to 67% and from 47% to 77% for sputum-smear-positive TB cases. The treatment success rate for private health facilities increased from 52% in 2010 to 80% in 2015. In 2013, contact screening was introduced, and the TB yield was 723 per 100,000-more than two times higher than the estimated national prevalence of 340 per 100,000. Contact screening contributed to identifying 2,509 child contacts of people with TB, and 76% of those children received isoniazid preventive therapy. The comprehensive urban DOTS program significantly improved service accessibility, TB case finding, and treatment outcomes in Kabul. Public- and private-sector involvement also improved treatment outcomes; however, the treatment success rate remains higher in private health facilities. While the treatment success rate increased significantly, it remains lower than the national average, and more efforts are needed to improve treatment outcomes in Kabul. We recommend that the urban DOTS approach be replicated in other countries and cities in Afghanistan with settings similar to Kabul.
Databáze: OpenAIRE
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