The correlation of ECHO findings of right cardiac pathologies with BNP, uric acid, and CRP in OSAS
| Autor: | Ömer ARAZ, Elif YILMAZEL UÇAR, Hüsnü DEĞİRMENCİ, Didem PULUR, Hamit ACEMOĞLU, Ednan BAYRAM, Fuat GÜNDOĞDU, Metin AKGÜN |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Heart Diseases medicine.drug_class Polysomnography Comorbidity Doppler echocardiography Sensitivity and Specificity chemistry.chemical_compound Tissue Doppler echocardiography Health Care Sciences and Services Internal medicine medicine.artery Natriuretic Peptide Brain OSAS echocardiography right cardiac pathologies BNP uric acid CRP medicine Natriuretic peptide Humans Sağlık Bilimleri ve Hizmetleri Sleep Apnea Obstructive medicine.diagnostic_test business.industry Sleep apnea General Medicine Middle Aged medicine.disease Echocardiography Doppler Uric Acid Obstructive sleep apnea chemistry ROC Curve Pulmonary artery Cardiology cardiovascular system Uric acid Female business |
| Zdroj: | Volume: 44, Issue: 5 832-838 Turkish Journal of Medical Sciences |
| ISSN: | 1300-0144 1303-6165 |
| Popis: | Right cardiac pathologies develop in patients with obstructive sleep apnea syndrome (OSAS) and in most patients there are no symptoms in the early stages of right cardiac disorders. We aimed to evaluate a possible relationship between B-type natriuretic peptide (BNP), blood uric acid, C-reactive protein (CRP), and the right cardiac pathologies in patients with OSAS, and the role of these parameters in the management of patients with OSAS. Materials and methods: A total of 98 subjects, 31 (31.6%) controls and 67 (68.4%) with OSAS, were included in the study. All the subjects underwent polysomnography, and standard and tissue Doppler echocardiography (ECHO) examinations. BNP, CRP, and blood uric acid levels were measured in all patients. Results: Upon evaluating the relationship between BNP and ECHO parameters, BNP levels were found to positively correlate with such ECHO parameters as pulmonary artery pressure. As for the association between CRP and ECHO findings, RV diameter exhibited a statistically significant positive correlation with them. Moreover, uric acid was found to statistically correlate positively with right atrium dimensions. Conclusion: BNP, CRP, and blood uric acid levels can be used as adjunctive parameters in the early diagnosis and follow-up of right heart pathologies in patients with OSAS. |
| Databáze: | OpenAIRE |
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