Type-specific seroprevalence of bluetongue in India during 2018 and 2019
| Autor: | Y. Narasimha Reddy, Kalyani Putty, G Naresh, Y Krishna Jyothi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Serotype
Veterinary medicine 040301 veterinary sciences 030231 tropical medicine Population Biology medicine.disease_cause SF1-1100 Virus 0403 veterinary science 03 medical and health sciences 0302 clinical medicine SF600-1100 medicine Seroprevalence education bluetongue education.field_of_study General Veterinary 04 agricultural and veterinary sciences Animal culture Vaccination serum neutralization test type-specific seroprevalence Superinfection Herd Flock competitive enzyme-linked immunosorbent assay Research Article |
| Zdroj: | Veterinary World, Vol 13, Iss 10, Pp 2092-2096 (2020) Veterinary World |
| ISSN: | 2231-0916 0972-8988 |
| Popis: | Background and Aim: Bluetongue (BT) is a major disease of sheep and goats and is endemic to India. It is known to cause significant economic losses to the sheep industry. The current study aimed to determine the type-specific seroprevalence of BT in sheep population of India during 2018-2019. Materials and Methods: Blood samples (n=405) were collected from 6 months to 1 year old sheep from six districts (Nalgonda, Karimnagar, Khammam, Mahabubnagar, Warangal, and Ranga Reddy) of Telangana state, India. Group- and type-specific seroprevalence (against BT virus [BTV] serotypes BTV-1, 2, 4, 5, 9, 10, 12, 16, 21, 23, and 24) was studied by competitive enzyme-linked immunosorbent assay and serum neutralization test, respectively. Results: Results showed an overall seroprevalence of 14.81% (n=60) with the highest seroprevalence of 50% in Khammam district. Seroprevalence of BTV-1, 2, 4, 5, 9, 10, 12, 16, 21, 23, and 24 was noted as 16.66%, 11.66%, 31.66%, 11.66%, 05%, 6.66%, 16.66%, 8.33%, 13.33%, 6.66%, and 16.66%, respectively. The majority of the sera neutralized more than 1 serotype, indicating superinfection or circulation of multiple serotypes in the sampled flocks. This mixed seroprevalence was observed in 43.33% of the sera with number of BTV serotype-specific antibodies ranging from two to eight in individual animals. Conclusion: Regular monitoring of circulating serotypes, especially in young herds, elucidates pattern of dominating serotypes in a particular area during a season. This knowledge can be applied to design appropriate vaccination strategies by including particular serotypes of virus as part of a multivalent vaccine for a particular period, in a particular area. |
| Databáze: | OpenAIRE |
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