Human Immunodeficiency Virus Infection: Does Highly Active Antiretroviral Therapy Influence Ear Nose Throat Manifestations?

Autor:	Jayashree Kanthila, Deviprasad Dosemane, Vijay Kumar, Deepak Madi
Rok vydání:	2018
Předmět:	medicine.medical_specialty business.industry Human immunodeficiency virus (HIV) medicine.disease_cause Antiretroviral therapy Oropharyngeal Candidiasis 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Otorhinolaryngology 030220 oncology & carcinogenesis Throat Internal medicine otorhinolaryngologic diseases medicine Original Article Surgery 030223 otorhinolaryngology business Prospective cohort study Nose Ear nose throat
Zdroj:	Indian Journal of Otolaryngology and Head & Neck Surgery. 70:555-558
ISSN:	0973-7707 2231-3796
Popis:	To study the change in trend of ear, nose and throat (ENT) manifestations in patients who were on treatment, before and after availability of highly active antiretroviral therapy (HAART). To find out the prevalence of ENT manifestations in human immunodeficiency virus (HIV) infected people who were on treatment, in the year of 2004 (before the availability of HAART) and in 2014 (after the availability of HAART). Design A combination of a retrospective and prospective study. Setting Anti Retroviral Therapy (ART) Center at Our Hospital. Subjects Patients with HIV infection on ART. Methods Retrospective review of case records of the patients visiting the center in the year 2004 and prospective study of the patients visiting in the year 2014 was conducted. Sample size was calculated as 200 in each group based on 95% confidence and 96% power. Convenience sampling was used in our study. The prevalence of ENT manifestations in HIV patients were found to be 86% in 2004 and 93% in 2014. Among ENT manifestations oropharyngeal manifestations were most common. Lesser the CD4 count more was the prevalence of disorders in oropharynx. Our study showed a high prevalence of ENT manifestations in HIV patients who were on treatment, irrespective of the gap of 10 years and introduction of HAART therapy. Most common ENT manifestation both in 2004 and 2014 was oropharyngeal candidiasis. Lesser the CD4 count more was the prevalence of disorders in oropharynx.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ead9945288ca8694cb1331af9fbd3ece https://doi.org/10.1007/s12070-018-1420-6 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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