Effect of urbanisation on asthma, allergy and airways inflammation in a developing country setting
| Autor: | Robert H. Gilman, Robert A. Wise, Patrick N. Breysse, Juan M. Combe, Guillermo Gonzalvez, Colin L Robinson, Nadia N. Hansel, Kathleen C. Barnes, A. Gómez, Lilia Cabrera, Lauren M. Baumann, William Checkley, Karina Romero |
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| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
Pulmonary and Respiratory Medicine
Spirometry Vital capacity Allergy Pediatrics medicine.medical_specialty corticosteroid spirometry respiratory tract inflammation environmental exposure atopy cigarette smoking urbanization Article allergy test Atopy FEV1/FVC ratio rhinitis forced vital capacity nitric oxide Environmental health Peru medicine controlled study Asthma particulate matter indoor air pollution medicine.diagnostic_test business.industry wheezing Environmental exposure asthma medicine.disease allergy forced expiratory volume urban population respiratory tract parameters Exhaled nitric oxide exhaled nitric oxide purl.org/pe-repo/ocde/ford#3.01.00 [https] eczema business bronchodilating agent urban area |
| Popis: | Background: Asthma is a growing public health problem in developing countries. However, few studies have studied the role of urbanisation in this phenomenon. It was hypothesised that children living in a peri-urban setting in Peru have higher rates of asthma and allergy than rural counterparts. Methods: 1441 adolescents aged 13-15 years were enrolled from two settings: a peri-urban shanty town in Lima (n=725) and 23 rural villages in Tumbes (n=716). Participants filled in questionnaires on asthma and allergy symptoms, environmental exposures and sociodemographics, and underwent spirometry, and exhaled nitric oxide (eNO) and allergy skin testing. Indoor particulate matter (PM) concentrations were measured in 170 households. Results: Lima adolescents had higher rates of lifetime wheezing (22% vs 10%), current asthma symptoms (12% vs 3%) and physician-diagnosed asthma (13% vs 2%; all p |
| Databáze: | OpenAIRE |
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