Respiratory Virus–Associated Severe Acute Respiratory Illness and Viral Clustering in Malawian Children in a Setting With a High Prevalence of HIV Infection, Malaria, and Malnutrition
| Autor: | Neil French, Meredith McMorrow, Marc Allain Widdowson, Nigel A. Cunliffe, Antonia Ho, Ingrid Peterson, Gugulethu Mapurisa, Naor Bar-Zeev, Thembi Katangwe, Maaike Alaerts, Dean Everett, Mavis Menyere, Ivan Mambule, Moses Chilombe, Robert S. Heyderman, Laura Newberry, David G. Lalloo, Nico Nagelkerke, Miguel A. Sanjoaquin, Neil Kennedy, Suzanne T. Anderson |
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| Rok vydání: | 2016 |
| Předmět: |
Male
0301 basic medicine Malawi Pediatrics medicine.medical_specialty Adolescent 030106 microbiology wc_503_5 qw_806 Article 03 medical and health sciences 0302 clinical medicine SDG 3 - Good Health and Well-being Nasopharynx wc_505 medicine Humans Immunology and Allergy 030212 general & internal medicine Child SDG 2 - Zero Hunger Intensive care medicine Respiratory Tract Infections 2. Zero hunger Respiratory tract infections business.industry Incidence (epidemiology) Absolute risk reduction Infant medicine.disease 3. Good health Vaccination Malnutrition Infectious Diseases Virus Diseases Child Preschool Relative risk Viruses ws_280 Respiratory virus Female business Malaria |
| Zdroj: | Peterson, I, Bar-Zeev, N, Kennedy, N, Ho, A, Newberry, L, San Joaquin, M A, Menyere, M, Alaerts, M, Mapurisa, G, Chilombe, M, Mambule, I, Lalloo, D G, Anderson, S T, Katangwe, T, Cunliffe, N, Nagelkerke, N, McMorrow, M, Widdowson, M-A, French, N, Everett, D & Heyderman, R S 2016, ' Respiratory virus-associated severe acute respiratory illness (SARI) and viral clustering in Malawian children in a setting with a high prevalence of HIV, malaria and malnutrition ', The Journal of Infectious Diseases . https://doi.org/10.1093/infdis/jiw426 Journal of Infectious Diseases JOURNAL OF INFECTIOUS DISEASES |
| ISSN: | 1537-6613 0022-1899 |
| Popis: | Background:\ud We used data from 4 years of pediatric severe acute respiratory illness (SARI) sentinel surveillance in Blantyre, Malawi, to identify factors associated with clinical severity and coviral clustering.\ud \ud Methods:\ud From January 2011 to December 2014, 2363 children aged 3 months to 14 years presenting to the hospital with SARI were enrolled. Nasopharyngeal aspirates were tested for influenza virus and other respiratory viruses. We assessed risk factors for clinical severity and conducted clustering analysis to identify viral clusters in children with viral codetection.\ud \ud Results:\ud Hospital-attended influenza virus–positive SARI incidence was 2.0 cases per 10 000 children annually; it was highest among children aged |
| Databáze: | OpenAIRE |
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