Predictors of seropositivity to herpes simplex virus type 2 in women
| Autor: | D W G Brown, P D Kell, B A Evans, M J Slomka, R A Bond, K D MacRae |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Sexual partner
Sexually transmitted disease medicine.medical_specialty Herpesvirus 2 Human Population Sexually Transmitted Diseases Dermatology Antibodies Viral Sex Factors Pelvic inflammatory disease medicine Prevalence Humans Pharmacology (medical) education Herpes Genitalis education.field_of_study business.industry Transmission (medicine) Obstetrics Public Health Environmental and Occupational Health Herpes Simplex Odds ratio medicine.disease Infectious Diseases Sexual Partners Immunology Multivariate Analysis Female Bacterial vaginosis business Follow-Up Studies |
| Zdroj: | International journal of STDAIDS. 14(1) |
| ISSN: | 0956-4624 |
| Popis: | Five hundred and twenty consecutive women newly attending a genitourinary medicine clinic who participated in a study of sexual behaviour were also tested for type-specific antibody to herpes simplex virus type 2; 135 (26%) were seropositive, of whom only 29 (21.5%) had had clinical evidence of genital herpes. Seropositive women were much more likely to have a past history of genital herpes (odds ratio [OR] 173). They were also more likely to be black non-UK born (OR 14), aged 30 years or over (OR 6), to have had 6-20 sexual partners (OR 3-4), especially from abroad (OR 12), to be unemployed (OR 6) or blue collar workers (OR 4), to have smoked cigarettes (OR 2) and to have practised peno-anal penetration (OR 5). Disease predictors included a past history of pelvic inflammatory disease (OR 63) and bacterial vaginosis (OR 3). Unexpected predictors were only one sexual partner (OR 5) and no non-regular partners (OR 5). Commencing intercourse before 16 years of age showed a protective effect (OR 0.2) and so did use of oral contraception (OR 0.5). Our findings show that infection with HSV-2 is associated with a wider range of morbidity and also emphasize the role of male sexual partner selection in the transmission of infection. |
| Databáze: | OpenAIRE |
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