The relationship between serum levels of total bilirubin and coronary plaque vulnerability
| Autor: | Yu-Ming Wang, Ke-Fu Zhu, Ning-Fu Wang, Yu-Qian Wang |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Male
China medicine.medical_specialty Acute coronary syndrome Bilirubin Coronary Artery Disease 030204 cardiovascular system & hematology Coronary Angiography Severity of Illness Index Gastroenterology Culprit Pathogenesis Coronary artery disease 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Internal medicine Intravascular ultrasound Severity of illness Odds Ratio medicine Humans Ultrasonography Interventional Retrospective Studies medicine.diagnostic_test business.industry Incidence General Medicine Odds ratio Middle Aged Prognosis medicine.disease Coronary Vessels Plaque Atherosclerotic chemistry 030220 oncology & carcinogenesis Female Cardiology and Cardiovascular Medicine business Biomarkers Follow-Up Studies |
| Zdroj: | Coronary Artery Disease. 27:52-58 |
| ISSN: | 0954-6928 |
| Popis: | OBJECTIVES Previous studies have reported that serum total bilirubin provides some protection against coronary artery disease (CAD); however, the relationship between serum levels of total bilirubin and culprit/target plaque vulnerability in patients with CAD remains unclear. In this study, we investigated the association between total bilirubin and tissue characterization of coronary plaque in patients with CAD. METHODS We enrolled 85 consecutive patients with CAD who underwent coronary angiography and intravascular ultrasound analyses [45 with acute coronary syndrome (ACS); 40 with stable angina pectoris (SAP)], and 45 age-matched participants served as the control group. Serum levels of total bilirubin in all participants were measured. The stability of the coronary plaque was compared between the ACS group and the SAP group, and the relationship between serum levels of total bilirubin and the features of coronary plaque was analyzed. RESULTS Serum levels of total bilirubin in the ACS group were significantly lower than those in the SAP and control groups (P |
| Databáze: | OpenAIRE |
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