Extradigestive Manifestation of Helicobacter Pylori Infection in Children and Adolescents
Autor: | Frank Y H Lin, Philip M. Sherman |
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Jazyk: | angličtina |
Rok vydání: | 2005 |
Předmět: |
Adolescent
Anemia Peptic Stomach Diseases Disease medicine.disease_cause Helicobacter Infections 03 medical and health sciences 0302 clinical medicine 030225 pediatrics medicine Humans lcsh:RC799-869 Child Growth Disorders Gastric Infection Anemia Iron-Deficiency Helicobacter pylori business.industry Gastroenterology General Medicine Iron deficiency medicine.disease Thrombocytopenic purpura 3. Good health Molecular mimicry Immunology 030211 gastroenterology & hepatology lcsh:Diseases of the digestive system. Gastroenterology Gastritis medicine.symptom business |
Zdroj: | Canadian Journal of Gastroenterology, Vol 19, Iss 7, Pp 421-424 (2005) |
ISSN: | 0835-7900 |
Popis: | Helicobacter pylori infection fulfills each of Koch's postulates as a human pathogen causing chronic active gastritis. Disease consequences that develop in a subset of infected subjects include peptic ulcerations, gastric adenocarcinoma and mucosa-associated lymphoid tissue lymphoma. More recently, multiple publications have advocated a role for H pylori infection in causing a variety of extraintestinal manifestations. Many of these reports suffer from being case reports or case series without adequate controls. As a result, purported manifestations may simply be coincidental in nature. On the other hand, increasing evidence supports H pylori infection as a cause of sideropenic (refractory iron deficiency) anemia. Moderate evidence supports H pylori gastric infection as a cause of some cases of immune thrombocytopenic purpura due to molecular mimicry. Guidelines should be adjusted in accordance with advancing knowledge in the field. |
Databáze: | OpenAIRE |
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