Transcutaneously measured near-infrared spectroscopic liver tissue oxygenation does not correlate with hepatic venous oxygenation in children
| Autor: | Joachim E. Fischer, Margrit Fasnacht, Markus Weiss, Hans Ulrich Bucher, Christian Balmer, Oskar Baenziger, Andreas C. Gerber, Gabriele Schulz |
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| Rok vydání: | 2002 |
| Předmět: |
Male
medicine.medical_treatment Hepatic Veins Inferior vena cava Liver tissue medicine Humans Child Vein Oxygen saturation Skin Cardiac catheterization Spectroscopy Near-Infrared business.industry Infant Venous oxygenation General Medicine Venous blood Oxygenation Oxygen Anesthesiology and Pain Medicine medicine.anatomical_structure Liver medicine.vein Child Preschool Anesthesia cardiovascular system Female business |
| Zdroj: | Canadian Journal of Anesthesia/Journal canadien d'anesthésie. 49:824-829 |
| ISSN: | 1496-8975 0832-610X |
| DOI: | 10.1007/bf03017416 |
| Popis: | To compare transcutaneous near-infrared spectroscopic (NIRS) measured liver tissue oxygenation with hepatic vein oxygen saturation (SvhO2) in children undergoing cardiac catheterization.A NIRS optode (containing an emitter and a receiver of near-infrared light) was placed directly below the right costal arch above the palpable liver in 40 children aged 0.02 to 7.28 yr (median: 1.8 yr). Spatially resolved spectroscopic measured tissue oxygenation index (TOI) was recorded using the NIRO-300. Paired blood samples from the hepatic vein were taken under radiological control for determination of SvhO2 in a co-oxymeter. TOI values were compared with hepatic vein oxygenation, with simultaneously obtained arterial oxygen saturation (SaO2), inferior vena cava SO2 and hemoglobin concentration using simple linear and multi-regression analysis.TOI values ranged from 35% to 73% (58.6 +/- 8.4%); SvhO2 from 32% to 80% (58.4 +/- 14.4%), and arterial SO2 from 54% to 100% (90.0 +/- 11.4%). TOI and hepatic vein oxygen saturation failed to correlate (r = 0.052/P = 0.752). A regression model containing arterial saturation (Delta R2 = 0.177) and the ratio of pulmonary to systemic resistance (Delta R2 = 0.095) explained 27.3% of the observed variance in TOI. In this model, hepatic vein oxygen saturation was no longer significant; explaining only 3.4% of the variance. No other variable retained a significant association.Transcutaneously measured NIRS tissue oxygenation with an optode placed over the palpable liver does not correlate with SvhO2. The value is dominated by non-hepatic variables such as arterial saturation and vascular resistances. |
| Databáze: | OpenAIRE |
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