A Novel Approach to Closure of Perineal Wounds During Abdominoperineal Resection
| Autor: | Sachin Vaid, Thomas Nicholson |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Fibrin Tissue Adhesive Perineum Hemostatics Fibrin Risk Factors Surgical Wound Dehiscence medicine Humans Abscess Digestive System Surgical Procedures Evisceration (ophthalmology) Aged Aged 80 and over Wound Healing biology Abdominoperineal resection Wound dehiscence business.industry Middle Aged medicine.disease Surgery Hemostasis biology.protein Female Median body business |
| Zdroj: | Archives of Surgery. 147:778 |
| ISSN: | 0004-0010 |
| DOI: | 10.1001/archsurg.2012.980 |
| Popis: | Abdominoperineal resection is associated with significant morbidity. The perineal wound poses a unique risk and complications are common, including skin breakdown, abscess, sinus tracts, perineal herniation, and evisceration. A 2-component fibrin sealant made from pooled human plasma has been proven to achieve hemostasis and tissue sealing. We report a case series of 5 consecutive patients in whom we used this fibrin sealant during perineal wound closure. Of our patients, 2 patients (40%) were diabetic and 4 patients (80%) received preoperative radiotherapy. The median body mass index was 32 (calculated as weight in kilograms divided by height in meters squared). The patients were at increased risk of perineal wound dehiscence and infection. Median follow-up was 6 months, and no patients had perineal wound complications. A fibrin sealant could be used as an alternative to more invasive procedures, such as flap reconstruction, in patients at high risk of perineal wound dehiscence. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|