Selecting Cost-Effective Antimicrobial Prophylaxis in Surgery: Are We Getting What We Pay for?
| Autor: | Allen B. Kaiser, Douglas S. Kernodle, Albert C. Roach |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty medicine.drug_class Premedication Antibiotics Cefazolin Pharmacy 030226 pharmacology & pharmacy 03 medical and health sciences 0302 clinical medicine Anti-Infective Agents medicine Humans Surgical Wound Infection Pharmacology (medical) Cefamandole General Pharmacology Toxicology and Pharmaceutics Intensive care medicine 030109 nutrition & dietetics business.industry Antimicrobial Tennessee Surgery Regimen Costs and Cost Analysis Pharmacy Service Hospital business medicine.drug |
| Zdroj: | DICP. 24:183-185 |
| ISSN: | 1042-9611 |
| DOI: | 10.1177/106002809002400214 |
| Popis: | The acquisition, administration, and infection-related expenses associated with the use of cefazolin or cefamandole during a prospective randomized comparison of antimicrobial prophylaxis in cardiac surgery were compared. Although the acquisition cost and administration charges related to the use of cefamandole were in excess of those incurred with cefazolin, differences in the charges associated with treating the wound infections that failed prophylaxis with each regimen made cefamandole the more cost-effective prophylactic agent (mean total of $766 per cefazolin recipient vs. $315 per cefamandole recipient). Analysis of prophylactic antimicrobials should include the expenses associated with “prophylactic failures.” The agent that is least expensive for the pharmacy may not be the most cost-effective choice for the institution. |
| Databáze: | OpenAIRE |
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