Disseminated infection to immune activation
| Autor: | Jill Yeager, Barbara E. Krenzer |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Chemotherapy
Hemophagocytic lymphohistiocytosis biology business.industry medicine.medical_treatment Immunosuppression General Medicine medicine.disease biology.organism_classification Pancytopenia medicine.anatomical_structure Case Studies Histoplasma Rheumatoid arthritis Immunology medicine Liver function Bone marrow business |
| Popis: | A 61-year-old woman with rheumatoid arthritis on chronic immunosuppression presented with fever. Laboratory studies demonstrated multiorgan failure with pancytopenia, elevation in liver function studies, and an elevated ferritin level, with a diagnosis of hemophagocytic lymphohistiocytosis confirmed on bone marrow biopsy. After initial treatment with chemotherapy, fungal blood cultures grew Histoplasma, prompting initiation of antifungal therapy, which resulted in successful treatment of Histoplasma-associated hemophagocytic lymphohistiocytosis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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