Mapping of quantitative trait loci for lactation persistency traits in German Holstein dairy cattle
| Autor: | Ernst Kalm, Norbert Reinsch, Jörn Bennewitz, Manfred Schwerin, Hauke Thomsen, Georg Thaller, M. Förster, B. Harder, Christa Kühn, F. Reinhardt, Georg Erhardt |
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| Rok vydání: | 2006 |
| Předmět: |
False discovery rate
Male Time Factors Population Quantitative Trait Loci Biology Quantitative trait locus Animal science Food Animals Lactation medicine Animals education Dairy cattle Genetics education.field_of_study Reproduction Haplotype food and beverages Chromosome Mapping Genetic Variation General Medicine Regression medicine.anatomical_structure Phenotype Performance ratio Haplotypes Animal Science and Zoology Cattle Female |
| Zdroj: | Harder, B, Bennewitz, J, Reinsch, N, Thaller, G, Thomsen, H, Kühn, C, Schwerin, M, Erhardt, G, Förster, M, Reinhardt, F & Kalm, E 2006, ' Mapping of quantitative trait loci for lactation persistency traits in German Holstein dairy cattle ', Journal of Animal Breeding and Genetics, vol. 123, no. 2, pp. 89-96 . https://doi.org/10.1111/j.1439-0388.2006.00577.x |
| ISSN: | 0931-2668 |
| Popis: | A whole genome scan to map quantitative trait loci (QTL) for persistency of milk yield (PMY), persistency of fat yield (PFY), persistency of protein yield (PPY) and persistency of milk energy yield (PEY) was performed in a granddaughter design in the German Holstein dairy cattle population. The analysis included 16 paternal half-sib families with a total of 872 bulls. The analysis was carried out for the first lactation and for the first three lactations combined using univariate weighted multimarker regression. Controlling the false discovery rate across traits and data sets at a level of 0.15 and treating the four persistency traits as different traits revealed 27 significant QTL. A total of 12 chromosomes showed significant QTL effects on a chromosomewise basis. The DGAT1 effect was highly significant for PPY and protein yield. A haplotype analysis using results of previous studies of the same design revealed a co-segregation of various persistency QTL and QTL affecting health traits like dystocia and stillbirth and functional traits like non-return rate 90 and somatic cell score. |
| Databáze: | OpenAIRE |
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