Concentrations of polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs) in human milk from Ireland: temporal trends and implications for nursing infant exposure

Autor: Nina Wemken, Margarete Houlihan, Stuart Harrad, Conor Noone, Colman O’Riordain, John J. Morrison, Claire Cellarius, Julie Tierney, Marie A. Coggins, Myra Keogh, Kathy Cleere, Sean Daly, Christina Tlustos
Přispěvatelé: Environmental Protection Agency (EPA), Ireland, Food Safety Authority of Ireland
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Popis: Aim: The elucidation of temporal trends in human exposure to polychlorinated biphenyls (PCBs) and 17 polychlorinated dibenzo-p-dioxins and furans (PCDD/Fs) since the previous Irish human milk surveys and to evaluate the impacts of legislative bans and restrictions on human exposure to these compounds. Methods: Concentrations of PCBs and 17 PCDD/Fs were measured in 16 pools of human milk collected from 92 Irish primiparas participating in the Irish EPA-funded ELEVATE project between October 2016 and April 2018, using Gas-Chromatography coupled with Mass spectrometry. Results: The geometric mean upper bound concentration of 16 pooled human milk samples [PCDD/Fs + dioxin-like (dl)-PCB TEQ; 4.5 ng kg-1 lipid weight] are on the lower end of those reported internationally. WHO-TEQ PCDD/Fs + dl-PCB are significantly lower (P This project (ELEVATE, reference 2016-HW-MS-8) is funded under the EPA Research Programme 2014-2020. The EPA Research Programme is a Government of Ireland initiative funded by the Department of Communications, Climate Action and Environment. We also acknowledge funding from the Food Safety Authority of Ireland. We gratefully acknowledge all the mothers who donated milk samples, as well as staff in University College Hospital Galway and Coombe Hospital, Dublin, for their help with this study. peer-reviewed
Databáze: OpenAIRE