Sildenafil (viagra) facilitates weaning of inhaled nitric oxide following placement of a biventricular-assist device
| Autor: | Bobby J. Heath, Vishal Sachdev, George Mychaskiw |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Adult
Male Pulmonary Circulation Phosphodiesterase Inhibitors Sildenafil Hypertension Pulmonary Nitric Oxide Piperazines Sildenafil Citrate Nitric oxide chemistry.chemical_compound medicine.artery Administration Inhalation medicine Humans Sulfones business.industry Hemodynamics medicine.disease Pulmonary hypertension respiratory tract diseases Anesthesiology and Pain Medicine Erectile dysfunction chemistry Purines Heart failure Anesthesia cGMP-specific phosphodiesterase type 5 Pulmonary artery cardiovascular system Milrinone Heart-Assist Devices business medicine.drug |
| Zdroj: | Journal of Clinical Anesthesia. 13:218-220 |
| ISSN: | 0952-8180 |
| Popis: | Sildenafil is a selective phosphodiesterase type 5 inhibitor used in the treatment of erectile dysfunction. We report the use of sildenafil to blunt the rebound pulmonary hypertension seen following withdrawal of inhaled nitric oxide (NO) and milrinone. The relatively long duration of sildenafil's action on pulmonary artery pressures and lack of systemic hemodynamic effect make it an attractive option to facilitate weaning of inhaled NO. |
| Databáze: | OpenAIRE |
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