Occupational exposure and airflow obstruction and self-reported COPD among ever-employed US adults using a COPD-job exposure matrix
| Autor: | Brent Doney, Steven M. Frenk, Cara N. Halldin, Janet M. Hale, Laura Kurth |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Chronic bronchitis medicine.medical_specialty National Health and Nutrition Examination Survey Job-exposure matrix Population Airflow obstruction Article 03 medical and health sciences Pulmonary Disease Chronic Obstructive Young Adult 0302 clinical medicine Risk Factors Internal medicine Occupational Exposure medicine Humans 030212 general & internal medicine education Aged education.field_of_study COPD business.industry Smoking Public Health Environmental and Occupational Health Odds ratio Middle Aged medicine.disease Nutrition Surveys 030210 environmental & occupational health Confidence interval United States respiratory tract diseases Occupational Diseases Spirometry Female Self Report business |
| Zdroj: | Am J Ind Med |
| Popis: | INTRODUCTION: This study examined the association of spirometry-defined airflow obstruction and self-reported COPD defined as self-reported doctor diagnosed chronic bronchitis or emphysema, with occupational exposure among ever-employed US adults. METHODS: Data were obtained from the National Health and Nutrition Examination Survey (NHANES) 2007–2008 to 2011–2012, a nationally representative study of the non-institutionalized civilian US population. Reported current and/or longest held job were used to create prevalence estimates and prevalence odds ratios (PORs) (adjusted for age, gender, race, and smoking status) for airflow obstruction and self-reported COPD by occupational exposure, determined using both NHANES participants’ selfreported exposures and eight categories of COPD job exposure matrix (JEM) assigned exposures. RESULTS: Significant PORs for airflow obstruction and self-reported COPD respectively were observed with self-reported exposure for ≥20 years to mineral dust (POR = 1.44; 95% confidence interval (CI) 1.13–1.85; POR = 1.69; 95% CI 1.17–2.43) and exhaust fumes (POR = 1.65; 95% CI 1.27–2.15; POR = 2.22; 95% CI 1.37–3.58). Airflow obstruction or self-reported` COPD were also associated with COPD-JEM assigned high exposure to mineral dust, combined dust, diesel exhaust, vapor-gas, sensitizers, and overall exposure. CONCLUSION: Airflow obstruction and self-reported COPD are associated with both self-reported and JEM-assigned exposures. |
| Databáze: | OpenAIRE |
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