Ameliorating effect of olive oil on fertility of male rats fed on genetically modified soya bean

Autor: Mohammad Abu Hilal, Ahmed K. Al-Ghamdi, Vishal G Shelat, Hatim A. Al-Abbadi, Thanaa A. El-Kholy, Hanan M. Sobhy, Dina M Qahwaji
Jazyk: angličtina
Rok vydání: 2015
Předmět:
Zdroj: Food & Nutrition Research
Food & Nutrition Research, Vol 59, Iss 0, Pp 1-6 (2015)
Food & Nutrition Research; Vol 59 (2015)
ISSN: 1654-661X
1654-6628
Popis: Background : Genetically modified soya bean (GMSB) is a commercialized food. It has been shown to have adverse effects on fertility in animal trials. Extra virgin olive oil (EVOO) has many beneficial effects including anti-oxidant properties. The aim of this study is to elucidate if addition of EVOO ameliorates the adverse effects on reproductive organs of rats fed on GMSB containing diet. Methods : Forty adult male albino rats (150–180 g) of Sprague Dawley strain were separated into four groups of 10 rats each: Group 1 – control group fed on basal ration, Group 2 – fed on basal ration mixed with EVOO (30%), Group 3 – fed on basal ration mixed with GMSB (15%), and Group 4 – fed on basal ration mixed with GMSB (15%) and EVOO (30%). This feeding regimen was administered for 65 days. Blood samples were collected to analyze serum zinc, vitamin E, and testosterone levels. Histopathological and weight changes in sex organs were evaluated. Results : GMSB diet reduced weight of testis (0.66±0.06 vs. 1.7±0.06, p
Databáze: OpenAIRE