Obesity is associated with vitamin D deficiency in Danish children and adolescents
| Autor: | Johanne Lind Plesner, Cilius Esmann Fonvig, Tenna Ruest Haarmark Nielsen, Oluf Pedersen, Julie T. Kloppenborg, Torben Hansen, Maria Dahl, Jens-Christian Holm |
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| Rok vydání: | 2017 |
| Předmět: |
Vitamin D/analogs & derivatives
Male Pediatric Obesity Adolescent Endocrinology Diabetes and Metabolism Denmark Population Parathyroid hormone Physiology 030209 endocrinology & metabolism body mass index Overweight vitamin D deficiency Childhood obesity 03 medical and health sciences 0302 clinical medicine Endocrinology medicine Vitamin D and neurology Prevalence parathyroid hormone Humans 030212 general & internal medicine Vitamin D education Child Vitamins/blood education.field_of_study calcium Vitamin D deficiency Anthropometry business.industry Odds ratio Vitamins medicine.disease Vitamin D Deficiency Denmark/epidemiology Pediatric Obesity/epidemiology Pediatrics Perinatology and Child Health Female medicine.symptom Vitamin D Deficiency/complications business Body mass index childhood obesity |
| Zdroj: | Plesner, J L, Dahl, M, Fonvig, C E, Nielsen, T R H, Kloppenborg, J T, Pedersen, O, Hansen, T & Holm, J C 2018, ' Obesity is associated with Vitamin D deficiency in Danish children and adolescents ', Journal of Pediatric Endocrinology and Metabolism, vol. 31, no. 1, pp. 53-61 . https://doi.org/10.1515/jpem-2017-0246 |
| ISSN: | 2191-0251 2017-0246 |
| DOI: | 10.1515/jpem-2017-0246 |
| Popis: | Background: Sufficient serum concentrations of vitamin D are required to maintain bone health during growth. The aims of this study were to determine whether vitamin D deficiency is more prevalent among children and adolescents with obesity compared to their normal weight peers and to identify clinical and biochemical variables associated with vitamin D deficiency. Methods: One thousand four hundred and eighty-four children and adolescents with overweight/obesity and 2143 population-based controls were recruited from the Danish Childhood Obesity Biobank. Anthropometric variables and fasting concentrations of serum 25-hydroxy vitamin D (25-OH-D), plasma parathyroid hormone (PTH), calcium and phosphate were assessed at baseline. Vitamin D deficiency was defined as serum 25-OH-D concentrations Results: A total of 16.5% of the children and adolescents with obesity (body mass index [BMI] standard deviation score [SDS]>2.33) exhibited vitamin D deficiency, with an odds ratio (OR) 3.41 (confidence interval [CI]: 2.27–5.71; p Conclusions: Vitamin D deficiency was common among Danish children and adolescents with obesity. The degree of obesity was independently associated with lower serum 25-OH-D concentrations. |
| Databáze: | OpenAIRE |
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