Serological Survey of Hantavirus in Inhabitants from Tropical and Subtropical Areas of Brazil

Autor: Alexandre Pereira, Renata Hurtado, Lilia Mara Dutra, Tiene Zingano Hinke, Marcos Lázaro Moreli, Tatiana Ometto, Monica Correia Lima, Edison Luiz Durigon, Luís Marcelo Aranha Camargo, Jansen de Araujo, Luiz Tadeu Moraes Figueiredo, Fábio Carmona de Jesus Maués, Aparecida Santo Pietro Pereira, Felipe Alves Morais, Sati Jaber Mahmud, Cristina Farah Tófoli, Marcello Schiavo Nardi
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Advances in Virology, Vol 2016 (2016)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Advances in Virology
ISSN: 1687-8647
1687-8639
Popis: Brazil has reported more than 1,600 cases of hantavirus cardiopulmonary syndrome (HPS) since 1993, with a 39% rate of reported fatalities. Using a recombinant nucleocapsid protein ofAraraquaravirus, we performed ELISA to detect IgG antibodies against hantavirus in human sera. The aim of this study was to analyze hantavirus antibody levels in inhabitants from a tropical area (Amazon region) in Rondônia state and a subtropical (Atlantic Rain Forest) region in São Paulo state, Brazil. A total of 1,310 serum samples were obtained between 2003 and 2008 and tested by IgG-ELISA, and 82 samples (6.2%), of which 62 were from the tropical area (5.8%) and 20 from the subtropical area (8.3%), tested positive. Higher levels of hantavirus antibody were observed in inhabitants of the populous subtropical areas compared with those from the tropical areas in Brazil.
Databáze: OpenAIRE
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