Spatio-angular filter (SAF) imaging device for deep interrogation of scattering media
| Autor: | Irina Schelkanova, Alexandre Douplik, Aditya Pandya |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Physics
0303 health sciences Photon Optical fiber business.industry Scattering Image processing 01 natural sciences Atomic and Molecular Physics and Optics Diffuse optical imaging Numerical aperture law.invention 010309 optics 03 medical and health sciences Optics Filter (video) law 0103 physical sciences Medical imaging business 030304 developmental biology Biotechnology |
| Zdroj: | Biomedical optics express. 10(9) |
| ISSN: | 2156-7085 |
| Popis: | Optical microscopy is limited to shallow interrogation depths as high-resolution imaging in scattering media is challenging. Current methods require complex and expensive experimental setup or suffer from low resolution. Through gating of photons exiting the scattering media using a restricted numerical aperture (NA) fiber optic plate (FOP), we establish a novel spatio-angular filter imaging device that allows deeper imaging in scattering media. Using dilutions of Intralipid (1-4 v/v%) and a USAF resolution target, it is shown that by reducing the NA of the FOP from 0.55 to 0.17, the interrogation depth improves ~2 times using trans-illumination. |
| Databáze: | OpenAIRE |
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