Molecular docking analysis of imine stilbene analogs and evaluation of their anti-aging activity using yeast and mammalian cell models

Autor:	Dashavantha Reddy Vudem, Rama Krishna Kancha, Rajasekhar Chikati, Raju Naini
Rok vydání:	2019
Předmět:	0301 basic medicine endocrine system diseases media_common.quotation_subject Imine Longevity Saccharomyces cerevisiae Resveratrol Biochemistry Antioxidants 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Sirtuin 1 Mammalian cell Stilbenes Humans Molecular Biology Cellular Senescence media_common Molecular Docking Analysis food and beverages Cell Biology Yeast Molecular Docking Simulation 030104 developmental biology chemistry Gene Expression Regulation 030220 oncology & carcinogenesis Histone deacetylase NAD+ kinase Imines K562 Cells hormones hormone substitutes and hormone antagonists
Zdroj:	Journal of receptor and signal transduction research. 39(1)
ISSN:	1532-4281
Popis:	The NAD+-dependent histone deacetylase SIRT1 was shown to be associated with aging and longevity. A stilbene, resveratrol (RV) was shown to exert anti-aging activity by stimulating the SIRT...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea848909847fda6c09d445de3b731af7 https://pubmed.ncbi.nlm.nih.gov/31132911 Zobrazit plný text záznamu