Verbal fluency dysfunction in euthymic bipolar patients: A controlled study

Autor: Márcia Britto de Macedo-Soares, Renata Sayuri Tamada, Cristiana Castanho de Almeida Rocca, Karla Mathias de Almeida, Beny Lafer, Cilly Kluger Isller, Angela Maria Schwartzmann, Clarice Gorenstein, José Antônio Amaral, Rodrigo da Silva Dias
Rok vydání: 2008
Předmět:
Zdroj: Journal of Affective Disorders. 107:187-192
ISSN: 0165-0327
DOI: 10.1016/j.jad.2007.07.013
Popis: Objective To study the executive functioning in euthymic bipolar patients in comparison to healthy controls and to examine the relationship between neuropsychological deficits and clinical variables. Methods Twenty-five euthymic bipolar patients and 31 controls underwent a battery of executive tasks including mental flexibility, inhibitory control and verbal fluency tests. Results There were no significant differences between bipolar patients and controls in relation to mental flexibility and inhibitory control. However, patients performed worse than controls on verbal fluency tests. Poor performances on the Stroop Test and the Hayling and Brixton Tests — part A were associated to lifetime occurrence of psychotic symptoms, prior number of episodes, and previous hospitalizations. Conclusions In our study, only verbal fluency tests differentiated bipolar euthymic patients from healthy controls. Patients who showed deficits in information processing speed and inhibitory control had more episodes and hospitalizations and lifetime occurrence of psychotic symptoms.
Databáze: OpenAIRE